Ighv Genes in Mcl
نویسندگان
چکیده
Alba Navarro, Guillem Clot, Cristina Royo, Pedro Jares, Anastasia Hadzidimitriou, Andreas Agathangelidis, Vasilis Bikos, Nikos Darzentas, Theodora Papadaki, Itziar Salaverria, Magda Pinyol, Xavier Puig, Jara Palomero, Maria Carmela Vegliante, Virgina Amador, Alejandra Martinez-Trillos, Lenka Stefancikova, Adrian Wiestner, Wyndham Wilson, Christiane Pott, Maria Jose Calasanz, Nicola Trim, Wendy Erber, Birgitta Sander, German Ott, Andreas Rosenwald, Dolors Colomer, Eva Giné, Reiner Siebert, Armando Lopez-Guillermo, Kostas Stamatopoulos, Sílvia Beà, Elías Campo
منابع مشابه
Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases.
We examined 807 productive IGHV-IGHD-IGHJ gene rearrangements from mantle cell lymphoma (MCL) cases, by far the largest series to date. The IGHV gene repertoire was remarkably biased, with IGHV3-21, IGHV4-34, IGHV1-8, and IGHV3-23 accounting for 46.3% of the cohort. Eighty-four of 807 (10.4%) cases, mainly using the IGHV3-21 and IGHV4-34 genes, were found to bear stereotyped heavy complementari...
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